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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7afb129b1145802ec3006987be3cbb2b7367e7d1eae7435f56dfaad5e464feb8' 
  AND token = 'cefGsqvrIG8j+SmmEN8PDinvrjTVwOO/pzxf6GyM7rM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}