SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b92007a9b4069f5f2f2499b21e152f75749b6991693e34bba9a2dadd5a9d604' 
  AND token = '4UAanK6v+ivgy9n1ofHkEI9yosOtArFmwS5PQTWqMAA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}