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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '731845f868fb1c7c34a3e8f6b2a2e49f09630c2571c6cd6364c4fd605863b1c3' 
  AND token = 'M0y4Z09rEaoEVI0kRq2IGRqSCmT4NDG7A1lr+r5BUnk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}