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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1186bed9d899eaef66ae982912f2a21b5f2dc0a9812d1d8d3f38365e71d6441e' 
  AND token = '55vg1/LZUM/aYqsxNPoskwFwCIKcaV2RBoTd/ayUFqQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}