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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1a5b1178e466b1f049f0afd4f18f25df22e09f7f9ad813513304170f9264420e' 
  AND token = 'AGX5tF/31igKtDAriOY1/K1VaansdAyO8aUhJV1y+F4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}