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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a89fd457acd5ddfbf70df1281d1048f8844e2a5a7160e14d166d5055d6d3a3c1' 
  AND token = 'ZDYz9mNCq8o8fQLHvpifQXAVyv4qqpO0JOH3obDfg2Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}