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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fc89d13728c079d49562fd5c16de4e8d3136c9c1725e4ba3a03028fb7edc41f5' 
  AND token = 'IaCwP5/coKmxh0fWUXwsjk6aUb/fZaNxLo6aHBONHF0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}