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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '276584a0ed4a4bd11c1be65a8d4072721988d907c900e997b3b138faeb5f1cb2' 
  AND token = '2xB6rjIMjxALEBbiyVR42GQ6o1C1YYDF4OQrS9kVXNw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}