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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '10eeb8a5ad5b019d9382953b4f8156594573b735302e933db4edef548e3307aa' 
  AND token = 'soiTCtB6ganJPOPf2M7LfV+ZFZDbyV7e6BKYHZpV9AQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}