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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c4c527ffe729aa096c15b9f4cb788139362e28cf84197cdc554bd4a65167f983' 
  AND token = 'pR63oe/bPysECKiOb6/coT00ABGslUdZlWJcnISNpGY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}