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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ff9ccd03ec202be29141f4b55157cac75817e65f1e4c53790286816bc8221f98' 
  AND token = 'heY5ThW0N7CbSMOHwGvnwmuO6wRo58oUy4CA+ENTbRQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}