SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1937aa5a9ea93ae3f2b58385b77f3a3249c86eb3c23f18510b01bb28a1b12efc' 
  AND token = 'jRDPh+r6R5aF2KVYmJDgLV5o4iK1MGvwIeCSVMgwV9s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}