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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c8d6fc983d7e923cb265688e276cca1deb7d90a40ac6c6452a0338b625046ebf' 
  AND token = '+ZIudzLrc9eg5yvUfGpIxEKT6zkvaTUJf93YoGzUGYI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}