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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '60289989270ab2a46cc650db89576a297efc858821cdf5b8e74a301202a665fe' 
  AND token = '9BSiUQpYxj3z5nMUhg2DuJxyn6p1iG/h3y0fYqTpZa4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}