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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7ec19e973eb8aaf25b3e2b8afa3686705bcaae1a9519a9df6cb4f648a7313f9b' 
  AND token = 'hUF8KLUg477Soc3mu6uHvtX1eYOrB6A+RSMAYGQLBmE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}