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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '91dea549b63a491ffcbbf2a1d10d3fa31427a1402138b4d73a8be6417780906b' 
  AND token = 'keOPGFcFSRo6bpP/wL7cACyvoz+9Gjj1kHCgXcIr3KY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}