SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9d44847c01abd89d11b2483d844628c36c10bcba4368c55aeefe9767c57e250e' 
  AND token = 'CgdexKVnYSnd8jqXDfowoBKMo0nVpAgVQWo8LD8GWUw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}