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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7c3890dadf18d487576245a852b8d034e07759b3c73c8a93d32fffaa8638f3ca' 
  AND token = '+vX0Dx8tMm6+27ens+uz+JaB6mtk0WQlVXN2TzpTwwk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}