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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b4d2706c2051d9a3b05c6462a4d06f33c0f8dd76281126f792e85fed17943c3' 
  AND token = 'CdsWNoX8K1m8WFb3oh9l4IfLYTVng22QYTQ1LrWlekc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}