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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '19ce3bbf407e2da8915f2a3bf3500f2fbbc05c30758a2a07e1aa2f5866ef4327' 
  AND token = 'qMteWrv8nubVSZKWANz1sC0Wxy2Uxs5+bKRlJxAZfwo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}