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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '888320f19fc036f5400c1e2cb2e26c89c746f52cbee9586dbe7dd7494bfd65f6' 
  AND token = 'eB14PYAEhU5C3MMFmrl7VHd/KazaaZl3jpm98S3KkzE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}