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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9f59184b91f6591e05842a0e55476194435e7e378ee856ee6c94afa48e02a0d4' 
  AND token = 'oOpvm/FCz12FjKKtF9hFoDj0mRIKgf9e12JE5heGrH4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}