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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f9218ad333ef5ad3afd7de60f9d9bd0b99e800220ea98591f4b1129c3763c7fb' 
  AND token = 'umGYtLbs/YkLPz4X9goct+C7pn/1xaqHDHHNUUJIs/E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}