SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fd492f9cfdb31becd74df773d2760ab7649c9f1bcd60eee579f4d57c6fa761ab' 
  AND token = 'tNO61YiW4qzQ6V5pqTltv9/eVbXvxG2OEe9tiV1OwCc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}