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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1a4cf8d8c4cd4d37a487bca33775cdbe3c1149dc66d6cc889a752b9a169e74c2' 
  AND token = 'LtKliyfDBvfhg9/XfqQq9GN0Gido9Dpg8vBKSXBDq7o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}