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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e4ea9931cb6b1bce99bcaf9b6da2e2205da38b06ed605b17dd11228c05aa2f67' 
  AND token = 'PZQZ00OlP88kR3TeDQu0Ct+AQpdJgDU9GOapjsXpE2Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}