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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2aca674bd85f4232f26909824ed9cc64b9e0918314d16ae58a78354b80903d01' 
  AND token = 'Bpoxwic+YRaeXozaZX1hbUUsFr1XSXum53sauIWXgTo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}