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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4bd0d165f4e6a891618497c1d860039b1a9e23d329ff0136a37ce2ae8c3b3345' 
  AND token = 'YMJgSX7l4IM8m2j8p1Cw8R1N9lbGxt2SUa3x8gVwyT8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}