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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e9d99cef5197dad9d74da5203ea6d96e5e5adb8c0128668051e81b012cd25753' 
  AND token = 'E858DP2Zv7fFQ0wC/jh4AMQd+n6QwEO2oM1Mjz/+B/s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}