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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0136f5fc95c049be170914d1759a1affdec77e8bc3b34a99438bcb51f3968c16' 
  AND token = 'xj9uQO0uOE1xYY7XEJO37GxN5gTnqJNrZjRHDlRLdgU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}