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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f7ee2d3fb29958811897a72581d6b380bec452bd23e2239873a353322c2fc4f5' 
  AND token = '1NUUPhFVvuEaXgKgFSJmlMsIKHQhOkzeIbMou0nfs9k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}