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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '043b3038757c29c4cfe332df5216c2d101196f52ca91afc2e5d8a3b671c4182f' 
  AND token = 'nV9USCTdIG/slmZ2OBaxKzCTgRl/ARDa8NSsIc+6czw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}