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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ba61a9cb2066959324f1792ed939c01566ba305e913e60ea7f44539a33a2d249' 
  AND token = 'alpUuAVDQcr7m0oiyyNAmZA8z1vUhNJ9sIZwN50LhT0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}