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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0421960651840049794677149c4db6b62c3d3bb4342c3bb9e2fca2776e50f3b2' 
  AND token = 'IPN7pjnObvDBw1pcbrkTs4Z7pTrCw4wGlaz1YuDfXfc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}