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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1176cb880966cd6b14eafe4a37dce626853303bbfab816dbf62acec4b86caa4f' 
  AND token = 'naAqX3B96sn/75J0+Ng1XXz50nmJw0tK492XnSztH4Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}