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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7209df4690eb057160f9b14717fdefed29a86d63f379d575835e92c4b57b6a02' 
  AND token = 'UqW4eiyIo1zRji9Rg7jUgwHeHPt5Ryh8lK48j446rr8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}