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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cf1b627e52d2b7a55f18bedbb91c42e038216e43876527613c6d15743bf0ec28' 
  AND token = '0iCE2mLovq1LT3xIIf2tv7aKQygH8D06USFd7KhR0l4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}