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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '26a189779ef257baf6f29dcbab82ef80717dab9a49dfad4af36206b796af99ec' 
  AND token = 'cUk44g3uJe4jdywakKUecECCK0TyILaKFWeSZTZb8zQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}