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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c84c999412d7490a8dbcd649a69942fc5e934f47c8e6b87e306122a82f906a21' 
  AND token = 'o75JXhA2kIn1e1hbWkG0PdltKRMjieWdaQrj1vg0wH0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}