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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3af5b9f9798257330299b65e228f55875857ae005e9adb93f42ec9d12b2d16c6' 
  AND token = 'S+M025BgYS1+XyCMBEo43u0Fb5B6n1OI47pAeVFLPRs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}