SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0eb20e2d8c349401ffbb1de8fe5abcafd9f3b97bb5261a4297ffeef443c7d9a6' 
  AND token = 'MHXKd4Ze2c1IV9/Wf+KdJ/m6XZ4ZQPhG+XQx2nazaHA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}