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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2134b7f69009201c409a1d5300920f14f5d77ff5e20459ab46e24656e12da78f' 
  AND token = 'jcljqGFr2Nx0etWcd1KUGFLaMH8qL4Qa04IAgIt54vs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}