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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e28e6da999f4ee66356449997f82e83eb73775f013867eed7021877eede2f124' 
  AND token = 'Xtr8kI3IfdAiwvoFE58rTNs5pCsKL3W7SS4FuwAgAn4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}