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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5036823090682ac0eaad2e284bf68480d397bf76c2c0c2c5eac8c05f2272b119' 
  AND token = 'Yj5PmBM1Yl+XAWc9WgAzsETMJM92znNiGzIKPiW3nuc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}