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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ae60a258e48cc94eca2ca131c26a9301db78d29f260dd225a39ae5669f42f911' 
  AND token = 'Ohe1uG6F1CV2ocJWYcSTNZyzr6kqDNQwZd9Bz7uGS5g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}