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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c87b8369c1a44fa190155c84db937fdf73f1a55188445882996e30dc073dad3f' 
  AND token = 'KSxBhNT4Qi1Cg64EW/tVmUkR4t57NmV5//qfETw3Tag=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}