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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c325f128719c281e1cb759476488fbc9229e74eaed6126ba5876d8079a15191' 
  AND token = 'vkeS3noQ+fJ9E8XIspCDbt9d4l+iFmyQ5/gSvfep2Ow=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}