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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c210e5e46cb27df4b595ef71d42fa2a2a99921718864bd585e89018a95e3bb9' 
  AND token = '2CAusDEO0EYD5QbKuGHB5Taz26H5bOLdl5MfFVRk1oc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}