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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8287e209ee5c820b3dc831124358378927cbd1770961bf8a90c74e259fb0c971' 
  AND token = 'YN18+x5+KqfeD+M7NdjxWTNAJZxS2b11iov0XNGi0QM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}