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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e34fdc6548f04d6ecb855598603d8520b2138307736a6c1517a61f1ab04a9443' 
  AND token = 'xnudAr4gtL161tT/cXXqMLFVnDqhCdykfU2UdEcYkQY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}